Transcranial magnetic stimulation for treatment of selected conditions

Status: Decision completed

Policy context

Transcranial magnetic stimulation (TMS) is a noninvasive technique used to stimulate areas of the brain associated with mood regulation and delivers intense magnetic pulses into the brain. Certain studies and meta-analyses suggest that TMS may be an effective treatment for various conditions.

Primary criteria ranking

  • Safety = Low/Medium
  • Efficacy = Medium/High
  • Cost = Medium/High
Documents

Related topics:

Assessment timeline

  • Draft key questions published: July 8, 2022
    • Public comment period: July 8 to July 22, 2022
  • Final key questions published: August 23, 2022
  • Draft report published: January 5, 2023
    • Public comment period: January 5 to February 6, 2023
  • Final report published: February 21, 2023
  • HTCC public meeting: March 17, 2023
  • Draft findings and decision published: March 31, 2023
    • Public comment period: March 31 to April 14, 2023
  • Final findings and decision published: June 29, 2023

 

All future dates are estimates and subject to change.

Background

Mental health conditions affect a large proportion of the American population, according to several nationally representative surveys. Over 14 million adults (14.2%) are estimated to have serious mental illness (SMI), in which the mental illness causes serious functional impairment interfering with one or more major life activities. Individuals suffering these conditions often experience decreased quality of life and impaired function across physical, emotional, and social domains.

Current treatment approaches for behavioral health disorders often begin with psychotherapy, pharmacotherapy, or both. However, many people do not achieve adequate clinical responses after the initial treatment attempt, and second and third-line medications or procedures (e.g., electroconvulsive therapy (ECT)) carry risk of adverse side effects that many individuals do not tolerate. Transcranial magnetic stimulation (TMS) is a noninvasive neuromodulation technique that has been FDA approved for some behavioral health and neurologic conditions. There is a growing evidence base that TMS may be efficacious, with fewer or more tolerable side effects, and has led to growing interest in applying TMS to a broad set of conditions, most often those deemed treatment resistant.

This health technology assessment (HTA) reviews the efficacy, safety, and cost-effectiveness of TMS to assist the State of Washington's Health Technology Clinical Committee (HTCC) in determining coverage of TMS for the following selected behavioral health disorders: depression; anxiety disorders including generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD);  posttraumatic stress disorder (PTSD); and addiction disorders including tobacco use disorder and substance use disorder (SUD).